Description

1-[3-(Trifluoromethyl)Phenyl]Propane-1,2-Diol is a high-value fluorinated aromatic diol building block. This compound is prized for its unique trifluoromethylphenyl group, which imparts desirable properties such as enhanced lipophilicity and metabolic stability to target molecules. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the synthesis of active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel therapeutic agents, including potential CNS drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Polymer Chemistry: Acts as a monomer or chain extender for creating specialty polyesters and polyurethanes with improved chemical resistance.
• Organic Synthesis Building Block: Employed in asymmetric synthesis and medicinal chemistry research to introduce the 3-(trifluoromethyl)phenyl moiety.
• Advanced Material Research: Investigated for use in the development of novel organic electronic materials and coatings.

Basic Information

Product Name	1-[3-(Trifluoromethyl)Phenyl]Propane-1,2-Diol
CAS No.	15814-25-2
Molecular Formula	C10H11F3O2
Molecular Weight	220.19 g/mol
Synonyms	3-(Trifluoromethyl)phenyl-1,2-propanediol; 1,2-Propanediol, 1-[3-(trifluoromethyl)phenyl]-; α-(3-Trifluoromethylbenzyl)glycerol; 1-(3-Trifluoromethylphenyl)-1,2-propanediol; (RS)-1-[3-(Trifluoromethyl)phenyl]propane-1,2-diol; 3'-(Trifluoromethyl)phenyl-1,2-propanediol; 1-(m-Trifluoromethylphenyl)-1,2-propanediol
EINECS	Contact for details

Quality Control

Our 1-[3-(Trifluoromethyl)Phenyl]Propane-1,2-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.