Description

6,7-Difluoroquinoline is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine atoms can dramatically alter biological activity and metabolic stability. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Serves as a building block for creating organic semiconductors, liquid crystals, and advanced polymers.
• Fluorinated Ligand Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create fluorescent tags and molecular probes for diagnostic and research applications.

Basic Information

Product Name	6,7-Difluoroquinoline
CAS No.	127827-50-3
Molecular Formula	C9H5F2N
Molecular Weight	165.14 g/mol
Synonyms	Quinoline, 6,7-difluoro-; 6,7-Difluoroquinoline; 127827-50-3; 6,7-Difluoro-quinoline; 6,7-Difluorochinolin; 6,7-Difluoro-1-azanaphthalene
EINECS	Contact for details

Quality Control

Our 6,7-Difluoroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.