Description

Ro 41-1049 Hcl Mao-A Inhibitor is a potent and selective inhibitor of monoamine oxidase A (MAO-A), a key enzyme in neurotransmitter metabolism. This compound is a critical research tool for investigating the role of MAO-A in neurological and psychiatric disorders. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and contract research organizations (CROs) focused on neuroscience, depression, and anxiety research.

Application

• Neuroscience Research: Fundamental studies on neurotransmitter dynamics, particularly serotonin and norepinephrine, in the central nervous system.
• Psychiatric Disorder Modeling: Used in preclinical research to create models and investigate the pathophysiology of depression and anxiety.
• Drug Discovery & Development: Serves as a reference standard and pharmacological tool in screening assays for novel antidepressant candidates.
• Biochemical Assay Development: Employed to validate and optimize in vitro enzyme inhibition assays for MAO-A activity.
• Academic & Institutional Research: Supports basic science investigations into enzyme kinetics and receptor pharmacology.
• Toxicology Studies: Used to study the effects of MAO-A inhibition and potential drug interactions (e.g., serotonin syndrome).

Basic Information

Product Name	Ro 41-1049 Hcl Mao-A Inhibitor
CAS No.	127500-84-9
Molecular Formula	C₁₃H₁₃ClN₂O
Molecular Weight	248.71 g/mol
Synonyms	Ro 41-1049; Ro-41-1049; Ro 41-1049 hydrochloride; 5-(Aminomethyl)-3-(2,4-dichlorophenyl)-1,3-oxazolidin-2-one hydrochloride; (R)-5-(Aminomethyl)-3-(2,4-dichlorophenyl)oxazolidin-2-one hydrochloride; MAO-A Inhibitor Ro 41-1049; Monoamine Oxidase A Inhibitor Ro 41-1049
EINECS	Contact for details

Quality Control

Our Ro 41-1049 Hcl is produced under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assessment, and impurity profiling. Certificates of Analysis (COA) detailing specific results for each parameter are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.