Description

2,4-Difluoro-5-Nitrobenzaldehyde is a high-purity aromatic aldehyde building block characterized by its strategically positioned fluorine and nitro substituents. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, enabling the introduction of key functional groups into complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing difluorophenyl motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, where the nitro and aldehyde groups serve as handles for further chemical modification.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, and photoactive compounds.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2,4-Difluoro-5-Nitrobenzaldehyde
CAS No.	127228-77-7
Molecular Formula	C7H3F2NO3
Molecular Weight	187.10 g/mol
Synonyms	5-Nitro-2,4-difluorobenzaldehyde; 2,4-Difluoro-5-nitrobenzaldehyde; Benzaldehyde, 2,4-difluoro-5-nitro-; 2,4-Difluoro-5-nitro-benzaldehyde; 127228-77-7
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoro-5-Nitrobenzaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.