Description

Ethanone, 1-Bicyclo[2.2.1]Hept-2-Yl-2,2-Difluoro-, Endo- (9Ci) is a specialized fluorinated organic compound featuring a norbornane (bicyclo[2.2.1]heptane) core, which imparts unique steric and electronic properties. This compound is valued for its role as a key advanced pharmaceutical intermediate (API) and a versatile building block in fine chemical synthesis. It is primarily sought by R&D and production teams in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug molecules, particularly those requiring a rigid, fluorinated scaffold for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the difluoroacetyl group and norbornane structure contribute to biological activity.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced materials with specific fluorinated characteristics.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for asymmetric catalysis, leveraging its defined stereochemistry (endo- configuration).
• Fluorine Chemistry Studies: A valuable reagent for academic and industrial research exploring new C-F bond formation reactions and the properties of fluorinated compounds.

Basic Information

Product Name	Ethanone, 1-Bicyclo[2.2.1]Hept-2-Yl-2,2-Difluoro-, Endo- (9Ci)
CAS No.	127119-04-4
Molecular Formula	C9H10F2O
Molecular Weight	172.17 g/mol
Synonyms	1-(2,2-Difluoroacetyl)bicyclo[2.2.1]heptane (endo-); 2,2-Difluoro-1-(2-norbornyl)ethanone; endo-1-Bicyclo[2.2.1]hept-2-yl-2,2-difluoroethanone; 1-Norbornan-2-yl-2,2-difluoroethanone; Difluoro(2-norbornyl)methyl ketone; endo-2,2-Difluoronorbornan-1-yl methyl ketone; 127119-04-4; 1-Bicyclo[2.2.1]hept-2-yl-2,2-difluoroethanone
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-Bicyclo[2.2.1]Hept-2-Yl-2,2-Difluoro-, Endo- (9Ci) adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and GC-MS, NMR for structural confirmation, to ensure it meets exacting R&D and production specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to strong alkali and fluoride ions; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.