Description

γ-Cyclodextrin Sulfate is a chemically modified derivative of γ-cyclodextrin, characterized by the introduction of sulfate groups onto its macrocyclic oligosaccharide structure. This modification significantly enhances its solubility in aqueous media and imparts strong anionic properties, making it a powerful and versatile complexing and solubilizing agent. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors who require advanced molecular encapsulation and chiral separation capabilities.

Application

• Pharmaceutical Formulation: Used as a solubility enhancer and stabilizer for poorly water-soluble active pharmaceutical ingredients (APIs) through inclusion complex formation.
• Chiral Separation: Serves as a chiral selector in capillary electrophoresis (CE) and high-performance liquid chromatography (HPLC) for the resolution of enantiomers in drug development and quality control.
• Biochemical Research: Employed in protein stabilization studies, enzyme activity modulation, and as a tool for investigating protein-ligand interactions.
• Drug Delivery Systems: A functional excipient in the design of controlled-release and targeted delivery systems due to its anionic charge and host-guest chemistry.
• Analytical Chemistry: Acts as a buffer additive or mobile phase modifier to improve separation efficiency and peak shape in various chromatographic techniques.
• Catalysis: Can be utilized to create supramolecular catalytic systems where the sulfated cavity provides a unique microenvironment for chemical reactions.

Basic Information

Product Name	γ-Cyclodextrin Sulfate
CAS No.	126881-41-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	γ-Cyclodextrin Sulfate; Sulfated γ-Cyclodextrin; γ-Cyclodextrin Sulfate Sodium Salt; γ-CD Sulfate; Cycloheptaamylose Sulfate; γ-CD-SO4; S-γ-CD; Sulfobutyl Ether γ-Cyclodextrin (related derivative)
EINECS	Contact for details

Quality Control

Our γ-Cyclodextrin Sulfate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, degree of substitution (DS), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical applications, ensuring reliable performance in your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect product performance and stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0%
Degree of Substitution (DS)	Contact for details
Water Content (KF)	≤ 10.0 %
Residue on Ignition (Sulfated Ash)	Contact for details
pH (in solution)	Contact for details
Heavy Metals	< 20 ppm
Microbial Limits	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.