Description

Cathepsin D Inhibitor CAS NO 126731-59-7 is a potent and selective small molecule inhibitor of the aspartic protease cathepsin D, a key enzyme implicated in protein degradation and cellular signaling pathways. This compound is an essential research tool for elucidating the role of cathepsin D in disease progression, particularly in oncology, neurodegenerative disorders, and inflammatory conditions. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies for target validation, mechanism-of-action studies, and high-throughput screening campaigns.

Application

• Biomedical Research: Fundamental tool for studying the physiological and pathological functions of cathepsin D in cellular models.
• Oncology Research: Investigation of cathepsin D's role in tumor progression, metastasis, and apoptosis, aiding in the discovery of novel cancer therapeutics.
• Neurodegenerative Disease Studies: Research into the enzyme's involvement in Alzheimer's disease, Parkinson's disease, and other conditions associated with protein aggregation.
• Inflammation and Immunology: Exploration of cathepsin D's function in antigen presentation and immune cell activation.
• Drug Discovery & Development: Used as a reference standard and pharmacological probe in hit-to-lead optimization and preclinical studies.
• Biochemical Assay Development: Key component in developing enzymatic assays to screen for new inhibitor compounds.

Basic Information

Product Name	Cathepsin D Inhibitor
CAS No.	126731-59-7
Molecular Formula	C20H28N4O4
Molecular Weight	388.46 g/mol
Synonyms	Pepstatin A; Isovaleryl-Val-Val-Sta-Ala-Sta; (3S,4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-3-Methyl-1-oxo-2-[[(2S,3S)-3-methyl-1-oxo-2-[(2S)-2-pyrrolidinylcarbonyl]pentyl]amino]butyl]amino]-1-oxo-3-phenylpropyl]amino]-3-methyl-1-oxobutyl]amino]-3-hydroxy-6-methylheptanoic Acid; Iva-Val-Val-Sta-Ala-Sta; Cathepsin D Inhibitor I; Aspartic Protease Inhibitor
EINECS	Contact for details

Quality Control

Our Cathepsin D Inhibitor is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reproducible and reliable results for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.