Description

Topostin A2 CAS NO 126603-03-0 is a high-purity synthetic compound belonging to the retinoid class, known for its specific biological activity. This compound is critical for advanced research and development in life sciences, offering a reliable and consistent standard for experimental work. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on dermatology, oncology, and cell differentiation studies.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel retinoid-based therapeutics.
• Cell Biology & Biochemistry Studies: Used as a potent modulator of cell differentiation and proliferation in *in vitro* and *in vivo* research models.
• Dermatological Agent Development: Investigated for its efficacy in the formulation of treatments for skin conditions such as psoriasis, acne, and photoaging.
• Oncology Research: Employed in studies exploring the role of retinoid signaling pathways in cancer cell growth and apoptosis.
• Chemical Synthesis: Acts as a sophisticated building block for the synthesis of more complex retinoid analogs and derivatives.
• Analytical Standard: Provides a high-purity benchmark for quality control and method validation in analytical laboratories using HPLC, LC-MS, or NMR.

Basic Information

Product Name	Topostin A2
CAS No.	126603-03-0
Molecular Formula	C22H28O3
Molecular Weight	340.46 g/mol
Synonyms	9-cis-Retinoic Acid; Alitretinoin; Panretin; 9-CRA; (2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic Acid; LGD1057; NSC 608095; Retinoid AGN 192837
EINECS	Contact for details

Quality Control

Every batch of Topostin A2 is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including identity confirmation, purity assay, and impurity profiling, to ensure compliance with high-grade research standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach room temperature before opening to minimize condensation and moisture ingress.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.