Description

(R)-Cpp CAS NO 126453-07-4 is a high-purity, enantiomerically pure chemical compound, specifically the (R)-enantiomer of 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid. This compound is a potent and selective antagonist for the NMDA receptor, making it a critical research tool in neuroscience and pharmacology. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and fine chemical manufacturers focused on developing and studying neurological therapeutics, receptor mapping, and signal transduction pathways.

Application

• Neuroscience Research: As a selective NMDA receptor antagonist for studying glutamatergic neurotransmission, excitotoxicity, and synaptic plasticity.
• Pharmacological Development: A key reference standard and intermediate in the research and development of novel neuroprotective agents and CNS-targeting drugs.
• Biochemical Assays: Used in in vitro and in vivo studies to elucidate the role of NMDA receptors in learning, memory, and neurological disorders.
• Fine Chemical Synthesis: Serves as a chiral building block or a pharmacologically active moiety in the synthesis of more complex molecular entities.
• Diagnostic Tool Development: Potential use in developing assays and probes for receptor binding studies and diagnostic research.

Basic Information

Product Name	(R)-Cpp
CAS No.	126453-07-4
Molecular Formula	C9H17N2O5P
Molecular Weight	264.22 g/mol
Synonyms	(R)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic Acid; (R)-CPP; (R)-Cppene; (R)-4-(3-Phosphonopropyl)piperazine-2-carboxylic Acid; NMDA Receptor Antagonist (R)-CPP; (R)-Cpp Acid; (2R)-2-Carboxy-4-phosphonomethylpiperazine; (R)-Cppene Acid
EINECS	Contact for details

Quality Control

Our (R)-Cpp is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and the absence of critical impurities. Certificates of Analysis (COA) detailing specific results for assay, enantiomeric excess, and related substances are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.