Description

2-Amino-4-(4-Fluorophenyl)-6-Phenylnicotinonitrile is a high-value, multi-functional chemical intermediate with a complex heterocyclic structure. Its core value lies in its role as a versatile building block for synthesizing advanced pharmaceutical compounds and agrochemicals, enabling the introduction of key fluorinated and aromatic pharmacophores. This product is essential for R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients. The compound, identified by CAS No. 126202-91-3, is supplied under stringent quality control to ensure batch-to-batch consistency for critical synthesis pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorophenyl and aminonicotinonitrile motifs.
• Material Science: Potential monomer or precursor for specialty polymers, liquid crystals, or organic electronic materials requiring specific optoelectronic properties.
• Chemical Synthesis: Versatile scaffold for further functionalization in medicinal chemistry, enabling the creation of diverse compound libraries for high-throughput screening.
• Academic & Contract Research: Critical reagent for universities, government labs, and CROs (Contract Research Organizations) engaged in cutting-edge organic and medicinal chemistry research.

Basic Information

Product Name	2-Amino-4-(4-Fluorophenyl)-6-Phenylnicotinonitrile
CAS No.	126202-91-3
Molecular Formula	C18H12FN3
Molecular Weight	289.31 g/mol
Synonyms	2-Amino-4-(4-fluorophenyl)-6-phenyl-3-pyridinecarbonitrile; 4-(4-Fluorophenyl)-2-amino-6-phenyl-3-cyanopyridine; 6-Phenyl-2-amino-4-(4-fluorophenyl)nicotinonitrile; 2-Amino-4-(p-fluorophenyl)-6-phenylnicotinonitrile; 3-Cyano-4-(4-fluorophenyl)-6-phenyl-2-pyridinamine; 126202-91-3; Nicotinonitrile, 2-amino-4-(4-fluorophenyl)-6-phenyl-
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-4-(4-Fluorophenyl)-6-Phenylnicotinonitrile is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.