Description

Ethyl-D5 Paraben is a deuterated analog of the widely used preservative ethyl paraben, where five hydrogen atoms are replaced by deuterium (CAS No. 126070-21-1). This isotopic labeling makes it an essential internal standard for precise quantitative analysis in mass spectrometry, ensuring accurate measurement of paraben levels in complex matrices. It is primarily required by analytical laboratories and research institutions in the pharmaceutical, cosmetic, and food safety sectors for method development, validation, and regulatory compliance testing.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis of parabens in consumer products.
• Quantitative reference material for pharmacokinetic and metabolism studies in pharmaceutical research.
• Calibration standard for ensuring accuracy in cosmetic safety and quality control testing.
• Tracer compound in environmental monitoring to study the fate and transport of parabens.
• Critical reagent for developing and validating analytical methods compliant with FDA, EPA, or EU regulations.
• Use in stable isotope dilution assays to achieve high-precision results in complex biological samples.

Basic Information

Product Name	Ethyl-D5 Paraben
CAS No.	126070-21-1
Molecular Formula	C9D5H4O3
Molecular Weight	171.18 g/mol
Synonyms	Ethyl 4-hydroxybenzoate-d5; Ethyl paraben-d5; p-Hydroxybenzoic acid ethyl ester-d5; Ethylparaben-d5; Deuterated ethyl paraben; Ethyl 4-hydroxybenzoate (phenyl-D5); Benzoic acid, 4-hydroxy-, ethyl ester-d5; Ethyl paraben (ethyl-D5)
EINECS	Contact for details

Quality Control

Our Ethyl-D5 Paraben is manufactured under strict quality systems to ensure high isotopic purity and chemical stability, critical for its role as an analytical standard. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR and HPLC-MS, to confirm deuterium incorporation and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and assay is provided with every shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.