Description

L-659 877 is a high-purity, non-peptide chemical compound with significant research and development applications. This product is valued for its role as a potent and selective antagonist in pharmacological studies, particularly in the field of neuroscience and receptor characterization. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in the discovery of novel therapeutic agents. The compound is supplied with a guaranteed CAS No. 125989-12-0 to ensure traceability and material integrity.

Application

• Pharmacological Research: Used as a selective and potent antagonist in receptor binding and functional assays to study specific biological pathways.
• Neuroscience Studies: Critical for investigating the role of specific receptors in the central nervous system, aiding in the understanding of neurological disorders.
• Drug Discovery & Development: Serves as a key reference standard and tool compound in high-throughput screening and lead optimization processes.
• Biochemical Mechanism Elucidation: Employed to delineate signal transduction mechanisms and validate molecular targets in vitro and in vivo.
• Academic & Institutional Research: Supports basic scientific research in university and government laboratories for peer-reviewed publications.
• Biotech R&D: Integral to preclinical development pipelines for validating novel therapeutic approaches and target engagement.

Basic Information

Product Name	L-659 877
CAS No.	125989-12-0
Molecular Formula	C31H41N3O5S
Molecular Weight	567.74 g/mol
Synonyms	L-659,877; L659877; (2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-methylpentanoyl]amino]-1-oxo-3-phenylpropyl]amino]-4-(methylsulfanyl)butanoic Acid; N-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-methylpentanoyl]amino]-3-phenylpropanoyl]-L-methionine
EINECS	Contact for details

Quality Control

Every batch of L-659 877 is manufactured under strict quality management protocols and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for research use and are supported by a detailed Certificate of Analysis (COA) that includes data from HPLC, NMR, and mass spectrometry. We adhere to industry best practices to guarantee the material meets the high standards required for sensitive pharmacological applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and desiccated to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.