Description

Ro-31-7549 is a potent and selective chemical inhibitor widely utilized in biochemical and pharmacological research. This compound is valued for its specific activity as a protein kinase C (PKC) inhibitor, making it a critical tool for studying intracellular signaling pathways. It is primarily used by researchers and scientists in the pharmaceutical, biotechnology, and academic sectors for drug discovery, target validation, and mechanistic studies.

Application

• Biochemical Research: A key reagent for investigating the role of Protein Kinase C (PKC) isoforms in cellular processes such as proliferation, differentiation, and apoptosis.
• Drug Discovery & Development: Used in high-throughput screening (HTS) assays and target validation studies to identify and characterize novel therapeutic agents.
• Signal Transduction Studies: Essential for elucidating complex intracellular signaling cascades and understanding disease mechanisms related to PKC dysregulation.
• Academic Research: Employed in university and institutional labs for fundamental research in cell biology, neuroscience, and oncology.
• Pharmaceutical R&D: Supports the development of potential treatments for conditions like cancer, cardiovascular diseases, and neurological disorders where PKC is implicated.

Basic Information

Product Name	Ro-31-7549
CAS No.	125313-65-7
Molecular Formula	C24H21N3O4
Molecular Weight	415.44 g/mol
Synonyms	Ro 31-7549; Ro317549; 3-[1-[3-(Dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione; Bisindolylmaleimide IX; Protein Kinase C Inhibitor (Ro-31-7549)
EINECS	Contact for details

Quality Control

Our Ro-31-7549 is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee product integrity and support your research documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.