Description

Dehydro Tizanidine is a key pharmaceutical intermediate and chemical building block. This compound is of significant interest in the research and development of active pharmaceutical ingredients (APIs), particularly for its structural relationship to the muscle relaxant Tizanidine. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the synthesis of novel therapeutic agents and process chemistry optimization.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of Tizanidine hydrochloride and its related analogs.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new central nervous system (CNS) acting drugs.
• Process Chemistry: Serves as a building block in scaling up and optimizing manufacturing routes for pharmaceutical actives.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Chemical Synthesis: Utilized in organic synthesis for constructing complex heterocyclic structures relevant to pharmacology.

Basic Information

Product Name	Dehydro Tizanidine
CAS No.	125292-34-4
Molecular Formula	C₉H₈ClN₅S
Molecular Weight	253.71 g/mol
Synonyms	5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine; 2-Amino-4-(4,5-dihydro-1H-imidazol-2-ylamino)-6-chlorobenzothiazole; Dehydro Tizanidine Base; Tizanidine Impurity; Tizanidine Related Compound A; 6-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole
EINECS	Contact for details

Quality Control

Our Dehydro Tizanidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.