Description

Heptakis(2,3,6-Tri-o-''Octyl)-β-Cyclodextrin is a chemically modified cyclodextrin derivative where the hydroxyl groups on the β-cyclodextrin core are fully substituted with octyl chains. This modification significantly enhances its lipophilicity and ability to form stable inclusion complexes with a wide range of hydrophobic guest molecules in non-aqueous or biphasic systems. It is a critical material for researchers and formulators in the pharmaceutical, agrochemical, and specialty chemical industries seeking to improve the solubility, stability, or bioavailability of active ingredients. The compound is supplied under the CAS registry number 124761-95-1.

Application

• Pharmaceutical Research & Drug Delivery: As a solubility enhancer and stabilizer for poorly water-soluble drug candidates in pre-formulation studies and novel delivery systems.
• Catalysis & Chemical Synthesis: Employed as a phase-transfer catalyst or a molecular receptor in organic synthesis to facilitate reactions in non-polar solvents and improve selectivity.
• Analytical Chemistry: Used as a chiral selector or stationary phase modifier in chromatography (HPLC, GC) for the separation of enantiomers and complex mixtures.
• Agrochemical Formulations: To encapsulate hydrophobic pesticides or herbicides, enhancing their stability, controlled release, and efficacy.
• Fragrance & Flavor Encapsulation: For the stabilization and controlled release of volatile or sensitive aromatic compounds in consumer products.
• Material Science: As a building block or modifier in the development of advanced materials, sensors, and nano-assemblies.
• Environmental Remediation: Potential use in extraction processes or sensors for the detection and removal of organic pollutants from various matrices.

Basic Information

Product Name	Heptakis(2,3,6-Tri-o-''Octyl)-β-Cyclodextrin
CAS No.	124761-95-1
Molecular Formula	C~98~H~168~O~35~
Molecular Weight	~2000.3 g/mol
Synonyms	2,3,6-Tri-O-octyl-β-cyclodextrin; Octyl-β-cyclodextrin (fully substituted); Per(2,3,6-tri-O-octyl)-β-cyclodextrin; Heptakis(2,3,6-tri-O-octyl)-β-cyclodextrin; β-Cyclodextrin, 2,3,6-tri-O-octyl ether; TO-β-CD; Hydrophobic β-cyclodextrin derivative; 124761-95-1
EINECS	Contact for details

Quality Control

Our Heptakis(2,3,6-Tri-o-''Octyl)-β-Cyclodextrin is produced and tested under a rigorous quality management system. Each batch is analyzed to ensure identity, purity, and consistency. Key parameters monitored include assay (by HPLC or NMR), degree of substitution, and residual solvent levels. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We can support development projects requiring specific grades or custom specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which can affect performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC/NMR)	≥95% (typical)
Degree of Substitution (DS)	~21 (Theoretical for per-substitution)
Water Content (KF)	≤2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.