Description

Protein Kinase Inhibitor Peptide (1-31) is a synthetic, biologically active peptide sequence designed to specifically inhibit protein kinase activity. This compound is a critical research tool for studying intracellular signal transduction pathways, cell cycle regulation, and apoptosis. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for target validation, assay development, and preclinical studies.

Application

• Biochemical Research: Used as a specific inhibitor to study the role of protein kinases in cellular signaling cascades.
• Drug Discovery & Development: Serves as a reference standard and pharmacological tool for screening and validating novel kinase inhibitor candidates.
• Cell Biology Studies: Applied in vitro to investigate mechanisms of cell proliferation, differentiation, and programmed cell death (apoptosis).
• Enzyme Kinetics: Employed in enzymatic assays to determine inhibition constants (Ki, IC50) and understand substrate competition.
• Diagnostic Reagent Development: Potential use in the development of diagnostic kits for detecting kinase activity in pathological samples.

Basic Information

Product Name	Protein Kinase Inhibitor Peptide (1-31)
CAS No.	124695-91-6
Molecular Formula	C142H238N44O43
Molecular Weight	~3119.7 g/mol
Synonyms	PKI(1-31) Peptide; Protein Kinase Inhibitor (1-31); cAMP-dependent Protein Kinase Inhibitor (1-31); PKI Peptide (1-31); TTYADFIASGRTGRRNAIHD; Inhibitor Peptide of cAMP-dependent Protein Kinase; PKA Inhibitor Peptide (1-31); Synthetic PKI Fragment
EINECS	Contact for details

Quality Control

Our Protein Kinase Inhibitor Peptide (1-31) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.