Description

n-(Iodoallyl)Spiperone is a specialized iodinated derivative of the well-known dopamine antagonist spiperone, identified by CAS NO 124654-22-4. This compound serves as a critical intermediate and research tool in the development of novel radiopharmaceuticals and receptor-targeting agents. It is primarily required by pharmaceutical R&D laboratories, radiochemistry facilities, and academic institutions engaged in neuroscience and molecular imaging research for applications such as positron emission tomography (PET) tracer development and receptor binding studies.

Application

• Radiopharmaceutical Precursor: Key intermediate for the synthesis of iodine-123 or iodine-125 labeled PET and SPECT imaging agents targeting dopamine D2 receptors.
• Neurochemical Research: Used as a ligand or a synthetic building block in studies of neurotransmitter systems, receptor affinity, and binding kinetics.
• Molecular Probe Development: Serves as a template for creating novel diagnostic probes for neurological disorders such as Parkinson's disease and schizophrenia.
• Chemical Biology: Employed in the synthesis of activity-based probes for studying enzyme function and protein interactions in complex biological systems.
• Reference Standard: Used as an analytical standard in quality control and method development for pharmaceutical manufacturing and regulatory compliance.

Basic Information

Item	Details
Product Name	n-(Iodoallyl)Spiperone
CAS No.	124654-22-4
Molecular Formula	C23H25FIN2O2
Molecular Weight	504.36 g/mol
Synonyms	1-(4-Fluorophenyl)-4-[4-(2-iodoallyl)-1-piperazinyl]-1-butanone; Iodoallylspiperone; N-(2-Iodoallyl)spiperone; Spiperone, N-(iodoallyl)- derivative; IASP; Dopamine D2 receptor ligand derivative; Iodinated spiperone analog
EINECS	Contact for details

Quality Control

Our n-(Iodoallyl)Spiperone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term stability, consider storage at 2-8°C under inert atmosphere. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.