Description

Sodium Potassium Atpase Inhibitor 2 CAS NO 124541-52-2 is a potent and specific inhibitor of the Na+/K+-ATPase enzyme, a critical membrane protein responsible for maintaining cellular electrochemical gradients. This compound is a vital research tool for studying ion transport, cellular energetics, and the pathophysiology of conditions like heart failure and neurological disorders. It is primarily utilized by researchers and scientists in the fields of pharmacology, biochemistry, and molecular biology for mechanistic studies and drug discovery programs.

Application

• Biochemical Research: Fundamental studies on Na+/K+-ATPase enzyme kinetics, inhibition mechanisms, and ion transport physiology.
• Cardiovascular Research: Investigation of cardiac glycoside-like effects, inotropy, and models of heart failure and hypertension.
• Neuropharmacology: Research into neuronal excitability, neurotransmitter release, and the role of ion pumps in neurological diseases.
• Cell Biology: Probing cell volume regulation, intracellular signaling pathways linked to the sodium pump, and apoptosis.
• Drug Discovery: Serving as a reference standard or pharmacological tool in high-throughput screening for novel therapeutics targeting ion transport.
• Educational Use: As a specific reagent in university and institutional teaching laboratories for advanced physiology and pharmacology courses.

Basic Information

Product Name	Sodium Potassium Atpase Inhibitor 2
CAS No.	124541-52-2
Molecular Formula	C29H54N2O8
Molecular Weight	558.76 g/mol
Synonyms	Na+/K+-ATPase Inhibitor 2; 2,5-Dioxopyrrolidin-1-yl 4-[(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-2,6-dihydroxybenzoate; Ouabain Octahydrate Derivative; G-Strophanthin Analog; Cardiac Glycoside Research Compound
EINECS	Contact for details

Quality Control

Our Sodium Potassium Atpase Inhibitor 2 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and structural confirmation via spectroscopic methods, to ensure identity, potency, and consistency for research applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated). Due to its hygroscopic nature, the container should be kept sealed in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.