Description

Sodium Potassium Atpase Inhibitor 1 is a specialized biochemical research compound designed to selectively inhibit the Na+/K+-ATPase enzyme. This inhibition is critical for studying ion transport mechanisms, cellular energy metabolism, and related physiological pathways in both basic and applied research. It serves as an essential tool for researchers and scientists in the fields of pharmacology, neurobiology, and cardiovascular disease research, where precise modulation of this key membrane pump is required.

Application

• Biochemical Research: A key reagent for in vitro studies investigating the function and regulation of the Na+/K+-ATPase pump in cellular models.
• Pharmacological Screening: Used in high-throughput assays to identify and evaluate novel therapeutic agents targeting heart failure, hypertension, and neurological disorders.
• Neurobiology Studies: Employed to explore the role of ion gradients in neuronal excitability, neurotransmitter release, and the pathophysiology of conditions like epilepsy.
• Cardiovascular Research: Fundamental for studying cardiac glycoside binding sites and mechanisms of inotropy in cardiac muscle tissue.
• Cell Physiology: Utilized to manipulate intracellular sodium and potassium levels, enabling research into cell volume regulation, pH balance, and secondary active transport.
• Enzyme Kinetics: Serves as a specific inhibitor to determine kinetic parameters and inhibition constants (Ki) for the Na+/K+-ATPase enzyme in purified preparations.

Basic Information

Item	Detail
Product Name	Sodium Potassium Atpase Inhibitor 1
CAS No.	124541-50-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Na+/K+-ATPase Inhibitor 1; Sodium-Potassium Pump Inhibitor 1; Ouabain-like Inhibitor; Cardiotonic Steroid Analog; CAS 124541-50-0; ATPase Inhibitor (Na/K); 124541-50-0
EINECS	Contact for details

Quality Control

Our Sodium Potassium Atpase Inhibitor 1 is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including purity verification by HPLC and structural confirmation. A Certificate of Analysis (COA) detailing identity, purity, and assay results is provided with every shipment to support your research documentation and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is hygroscopic (moisture-sensitive); ensure the container is sealed in a dry environment after each use. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, Ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.