Description

5-(Trifluoromethyl)-2-Methoxypyridine-3-Carbaldehyde is a high-purity, versatile trifluoromethylpyridine derivative used as a key synthetic intermediate. Its value lies in the trifluoromethyl group, which imparts unique physicochemical properties critical for enhancing the metabolic stability and bioavailability of target molecules. This compound is primarily needed by pharmaceutical R&D and fine chemical synthesis teams for developing new active ingredients, particularly in agrochemical and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized organic materials and liquid crystals.
• Custom Synthesis & Contract Manufacturing: A key starting material for bespoke chemical manufacturing and scale-up projects.

Basic Information

Product Name	5-(Trifluoromethyl)-2-Methoxypyridine-3-Carbaldehyde
CAS No.	124432-66-2
Molecular Formula	C8H6F3NO2
Molecular Weight	205.13 g/mol
Synonyms	2-Methoxy-5-(trifluoromethyl)pyridine-3-carbaldehyde; 3-Formyl-2-methoxy-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2-methoxynicotinaldehyde; 2-Methoxy-5-trifluoromethylnicotinaldehyde; 124432-66-2; 5-Trifluoromethyl-2-methoxypyridine-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-2-Methoxypyridine-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.