Description

Cgs 21680A is a selective adenosine A2A receptor antagonist used extensively in pharmacological research. This compound is critical for studying the role of adenosine signaling in neurological and cardiovascular systems. It is primarily utilized by researchers in pharmaceutical R&D, academic institutions, and biotechnology companies focused on CNS disorders, inflammation, and Parkinson's disease models.

Application

• Neurological Research: Used as a key tool compound to investigate adenosine A2A receptor function in models of Parkinson's disease, addiction, and sleep regulation.
• Cardiovascular Studies: Employed in research exploring the modulation of coronary blood flow and cardiac protection mechanisms.
• Inflammation and Immunology: Applied in studies to understand the anti-inflammatory effects mediated by adenosine receptor blockade.
• Biochemical Assay Development: Serves as a reference standard in high-throughput screening (HTS) and receptor binding assays for drug discovery.
• Academic & Pharmaceutical R&D: A fundamental research chemical for target validation and preclinical studies in CNS and inflammatory conditions.

Basic Information

Item	Detail
Product Name	Cgs 21680A
CAS No.	124431-80-7
Molecular Formula	C15H21N7O6
Molecular Weight	395.37 g/mol
Synonyms	2-p-(2-Carboxyethyl)phenethylamino-5'-N-ethylcarboxamidoadenosine; CGS-21680A; CGS 21680 Hydrochloride; 2-[p-(2-Carboxyethyl)phenethylamino]-5'-N-ethylcarboxamidoadenosine; Adenosine A2A receptor agonist; CGS21680; 2-[[4-[2-[(2-Amino-9-β-D-ribofuranosyl-9H-purin-6-yl)amino]ethyl]phenyl]ethyl]propanoic acid
EINECS	Contact for details

Quality Control

Our Cgs 21680A is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research chemicals, ensuring reliability for your critical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.