Description

Triacetyldynemicin A is a chemically modified derivative of the potent enediyne antibiotic dynemicin A. This acetylated compound is a critical intermediate and research standard in the development of novel antitumor agents and molecular probes. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers focused on oncology drug discovery and chemical biology. The compound's unique structure makes it a valuable tool for studying DNA cleavage mechanisms and designing targeted cancer therapies.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis and structure-activity relationship (SAR) studies of novel enediyne-based anticancer agents.
• Chemical Biology: Used as a molecular probe to investigate DNA binding, cleavage mechanisms, and cellular targeting strategies.
• Oncology Drug Discovery: A reference standard for the development of antibody-drug conjugates (ADCs) and other targeted delivery systems leveraging the dynemicin warhead.
• Academic Research: Employed in university and institutional labs for fundamental studies on natural product biosynthesis, bioorganic chemistry, and mechanism of action.
• Bioconjugation Studies: Acts as a model compound for developing novel linker technologies and conjugation methodologies for potent payloads.

Basic Information

Product Name	Triacetyldynemicin A
CAS No.	124425-50-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Dynemicin A Triacetate; 1,2,7-Tri-O-acetyldynemicin A; Triacetylated Dynemicin A; Dynemicin A, 1,2,7-triacetate; Antibiotic Dynemicin A Triacetate
EINECS	Contact for details

Quality Control

Our Triacetyldynemicin A is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance records.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at -20°C under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.