Description

Methyl 5-(Trifluoromethyl)Nicotinate is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the trifluoromethyl group, which imparts unique electronic and metabolic properties to target molecules, enhancing their lipophilicity and stability. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitors and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the CF3 group improves biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of fluorinated organic electronic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Methyl 5-(Trifluoromethyl)Nicotinate
CAS No.	124236-38-0
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	5-(Trifluoromethyl)nicotinic acid methyl ester; Methyl 5-(trifluoromethyl)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 5-(trifluoromethyl)-, methyl ester; Methyl 5-trifluoromethylnicotinate; 5-Trifluoromethyl-nicotinic acid methyl ester; Nicotinic acid, 5-(trifluoromethyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 5-(Trifluoromethyl)Nicotinate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.