Description

2,4-Difluoro-3-(trifluoromethyl)bromobenzene is a high-purity, multi-functional fluorinated aromatic building block essential for advanced chemical synthesis. Its unique structure, featuring bromine and fluorine substituents, makes it a critical intermediate for introducing specific fluorinated motifs into target molecules. This compound is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic rings for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where fluorine atoms improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing compounds used in electronic display technologies and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for metal-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi, Stille) to form complex biaryl structures.
• Functional Material Research: Employed in R&D for creating novel polymers, ligands for catalysis, and specialty chemicals with tailored properties.
• Fluorine Chemistry Exploration: A valuable substrate for studying nucleophilic aromatic substitution and other reactions specific to fluorinated arenes.

Basic Information

Product Name	2,4-Difluoro-3-(trifluoromethyl)bromobenzene
CAS No.	124170-06-5
Molecular Formula	C7H2BrF5
Molecular Weight	260.99 g/mol
Synonyms	1-Bromo-2,4-difluoro-3-(trifluoromethyl)benzene; 3-Bromo-2,6-difluorobenzotrifluoride; 2,4-Difluoro-3-(trifluoromethyl)phenyl bromide; 2,6-Difluoro-3-(trifluoromethyl)bromobenzene; Benzene, 1-bromo-2,4-difluoro-3-(trifluoromethyl)-; 3-(Trifluoromethyl)-2,4-difluorobromobenzene
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoro-3-(trifluoromethyl)bromobenzene is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality systems are designed to support cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.