Description

Etomoxir-Coa is a high-purity biochemical inhibitor specifically designed for advanced metabolic research and pharmaceutical development. This compound is critical for studying and modulating fatty acid oxidation pathways, offering researchers a precise tool to investigate cellular energy metabolism. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on metabolic disorders, cardiology, and oncology.

Application

• Metabolic Pathway Research: A key inhibitor for studying mitochondrial fatty acid β-oxidation (FAO) in vitro and in vivo.
• Cardiovascular Disease Models: Used to investigate the role of energy substrate utilization in heart failure and ischemic injury.
• Cancer Metabolism Studies: Employed to explore the dependency of certain cancer cells on fatty acid oxidation for growth and survival.
• Pharmacological Tool Compound: Serves as a reference standard and active agent in high-throughput screening and drug discovery campaigns targeting metabolic enzymes.
• Biochemical Assay Development: Used in the development and validation of enzymatic assays for carnitine palmitoyltransferase I (CPT1) activity.
• Preclinical Research: Applied in animal models to validate therapeutic hypotheses related to metabolic switching.

Basic Information

Product Name	Etomoxir-Coa
CAS No.	124122-91-4
Molecular Formula	C29H48N7O19P3S
Molecular Weight	923.71 g/mol
Synonyms	Etomoxir Coenzyme A; Etomoxir-CoA; (2R)-2-[4-[2-[(2S,3S,4R,5R)-5-(6-Aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxyethyl-[3-[2-[2-(2-hexylcyclopropyl)acetyl]sulfanylethylamino]-3-oxopropyl]amino]-2-oxoethyl]hexylcyclopropaneacetate; Coenzyme A, S-[2-[2-(2-hexylcyclopropyl)acetyl]thio]ethyl] ester
EINECS	Contact for details

Quality Control

Our Etomoxir-Coa is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC purity analysis, NMR structural confirmation, and mass spectrometry (MS) for identity verification. A detailed Certificate of Analysis (COA) documenting purity, impurities, and solvent residues is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, keep under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.