Description

R-(+)-Etomoxir CAS NO 124083-20-1 is a high-purity, enantiomerically pure chemical compound that functions as a potent and specific inhibitor of carnitine palmitoyltransferase I (CPT1). This targeted action makes it a critical research tool for studying fatty acid oxidation and metabolic pathways. It is essential for researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors, particularly for metabolic disease research, drug discovery, and biochemical assay development.

Application

• Metabolic Research: A key tool for investigating the role of mitochondrial fatty acid β-oxidation in cellular energy metabolism and metabolic disorders.
• Cardiomyopathy Studies: Used in preclinical research to model and study heart conditions where energy substrate utilization is altered.
• Diabetes & Obesity Research: Employed to explore the link between fatty acid metabolism, insulin resistance, and related pathologies.
• Cancer Metabolism: Applied in oncology research to study how cancer cells rewire their metabolic pathways for growth and survival.
• Drug Discovery & Screening: Serves as a reference compound or positive control in high-throughput screening assays targeting metabolic enzymes.
• Biochemical Assay Development: Used to validate assays measuring CPT1 activity or fatty acid oxidation rates in vitro.

Basic Information

Product Name	R-(+)-Etomoxir
CAS No.	124083-20-1
Molecular Formula	C15H19NO3
Molecular Weight	261.32 g/mol
Synonyms	(R)-(+)-Etomoxir; (R)-Etomoxir; (+)-Etomoxir; R-Etomoxir; (2R)-2-[6-(4-Chlorophenoxy)hexyl]oxirane-2-carboxylic acid; POCA analogue; CPT1 Inhibitor
EINECS	Contact for details

Quality Control

Our R-(+)-Etomoxir is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure identity, potency, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our stringent specifications for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% (R-enantiomer)
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.