Description

S-(-)-Sulpiride-D3 is a deuterium-labeled isotopologue of the chiral benzamide derivative, sulpiride, specifically designed for use as an internal standard in quantitative analytical methods. This high-purity reference material is essential for ensuring accuracy and precision in mass spectrometry-based assays, eliminating variability and enhancing data reliability. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in pharmacokinetic studies, drug metabolism research, and bioanalytical method development.

Application

• Internal Standard for LC-MS/MS quantification of sulpiride in biological matrices (plasma, serum, urine).
• Metabolite tracing and pharmacokinetic (PK) studies in drug development.
• Bioanalytical method development and validation for regulatory submissions.
• Quality control and assurance in pharmaceutical manufacturing.
• Stable isotope dilution analysis for high-accuracy measurements.
• Research into the pharmacodynamics and mechanism of action of dopaminergic agents.

Basic Information

Product Name	S-(-)-Sulpiride-D3
CAS No.	124020-27-5
Molecular Formula	C15H20D3N3O4S
Molecular Weight	344.45 g/mol (deuterated form)
Synonyms	(S)-(-)-Sulpiride-D3; (-)-Sulpiride-D3; Levosulpiride-D3; (S)-5-(Aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2,3-dimethoxybenzamide-D3; DO 1563-D3; Dogmatil-D3; Eglonyl-D3; MLS-102-D3
EINECS	Contact for details

Quality Control

Our S-(-)-Sulpiride-D3 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for chemical and isotopic purity, NMR for structural confirmation, and mass spectrometry for isotopic enrichment verification. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with the rigorous standards required for analytical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.