Description

Collagenase Inhibitor I CAS NO 123984-15-6 is a potent and selective small molecule inhibitor of collagenase enzymes, specifically targeting matrix metalloproteinases (MMPs) involved in extracellular matrix degradation. This compound is crucial for research focused on understanding tissue remodeling, wound healing, and pathological processes such as cancer metastasis and arthritis. It is an essential biochemical tool for pharmaceutical R&D, academic research in cell biology and biochemistry, and the development of therapeutic agents targeting MMP activity.

Application

• Biochemical Research: Used as a specific inhibitor to study the role of collagenase enzymes (MMP-1, MMP-8, MMP-13) in in vitro and cell-based assays.
• Pharmaceutical Development: Serves as a reference standard and lead compound in the discovery and validation of novel anti-metastatic and anti-arthritic drugs.
• Dermatology & Cosmeceutical Research: Investigated for its potential to modulate collagen degradation in studies related to skin aging, photoaging, and wound repair.
• Inflammation & Immunology Studies: Applied in research models to elucidate the connection between MMP activity and chronic inflammatory diseases.
• Tissue Engineering: Utilized to control collagen turnover and scaffold stability in regenerative medicine applications.

Basic Information

Product Name	Collagenase Inhibitor I
CAS No.	123984-15-6
Molecular Formula	C₁₇H₁₉N₃O₄S
Molecular Weight	361.42 g/mol
Synonyms	N-Isobutyl-N-(4-methoxyphenylsulfonyl)glycyl hydroxamic acid; GM 6001; Ilomastat; Galardin; MMP Inhibitor I; Hydroxamate-based MMP inhibitor; NSC 405575; CAS 123984-15-6
EINECS	Contact for details

Quality Control

Our Collagenase Inhibitor I is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade research standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and related substances is provided with every shipment to guarantee batch-to-batch consistency and traceability for your research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.