Description

Fedotozine is a selective σ-1 receptor agonist, a high-purity pharmaceutical intermediate and research chemical with significant pharmacological interest. Its primary value lies in its role as a critical building block for developing novel therapeutic agents targeting the central nervous system and gastrointestinal disorders. This compound is essential for pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions engaged in neuropharmacology and visceral pain research.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the production of investigational drugs targeting σ-1 receptors.
• Neuropharmacology Research: Used as a reference standard and active compound in studies of pain modulation, neuroprotection, and psychiatric conditions.
• Visceral Sensitivity Studies: Applied in preclinical research for developing treatments for irritable bowel syndrome (IBS) and functional gastrointestinal disorders.
• Chemical Biology: Serves as a tool compound for elucidating σ-1 receptor signaling pathways and mechanisms of action.
• Analytical Reference Standard: Utilized in HPLC, LC-MS, and NMR for method development, validation, and quality control of related pharmaceutical products.

Basic Information

Product Name	Fedotozine
CAS No.	123618-00-8
Molecular Formula	C₁₉H₂₃ClN₂O₂
Molecular Weight	346.85 g/mol
Synonyms	Fedotozine; JO-1196; (+)-Fedotozine; (R)-Fedotozine; (R)-N-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-2-(1-pyrrolidinyl)ethylamine; 1-[(2R)-2-[[2-(3,4-Dichlorophenyl)ethyl]methylamino]ethyl]pyrrolidine; JO 1196
EINECS	Contact for details

Quality Control

Our Fedotozine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of specified impurities, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.