Description

(+)-7-Octylindolactam V is a potent and specific activator of protein kinase C (PKC), belonging to the class of indole alkaloid derivatives. This compound is a critical research tool for studying cellular signaling pathways, particularly those involving PKC isoforms. It is primarily utilized by researchers and scientists in the fields of pharmacology, biochemistry, and oncology for investigating cancer biology, neurodegenerative diseases, and signal transduction mechanisms.

Application

• Biochemical Research: As a selective PKC activator for studying enzyme kinetics, substrate specificity, and downstream signaling events in in vitro assays.
• Cell Biology Studies: For probing the role of PKC in cellular processes such as proliferation, differentiation, apoptosis, and secretion in various cell lines.
• Neuroscience Research: Investigation of PKC-mediated pathways in neuronal function, synaptic plasticity, and models of neurodegenerative disorders.
• Oncology Research: Exploration of PKC as a therapeutic target in cancer, studying its effects on tumor growth, metastasis, and drug resistance mechanisms.
• Pharmacology & Drug Discovery: Serving as a reference compound or positive control in high-throughput screening (HTS) campaigns to identify novel PKC modulators.
• Academic & Institutional Research: Fundamental research in universities and institutes focused on intracellular signaling and second messenger systems.

Basic Information

Product Name	(+)-7-Octylindolactam V
CAS No.	123597-54-6
Molecular Formula	C26H39NO3
Molecular Weight	413.60 g/mol
Synonyms	7-Octylindolactam V; Indolactam V, 7-Octyl-; Octylindolactam V; PKC Activator, (+)-7-Octylindolactam V; 7-n-Octylindolactam-V; L-Octylindolactam V; (3S,4aR,10bS)-8-Octyl-3-(phenylmethyl)-2,3,4,4a,5,6,10,10b-octahydro-1H-[1]benzoxepino[4,3-b]indol-9-ol
EINECS	Contact for details

Quality Control

Our (+)-7-Octylindolactam V is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (NMR, IR, MS), and chiral purity analysis, to ensure it meets the exacting standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.