Description

Arginine-Glycine-Aspartate-o-Methyltyrosine Amide is a specialized peptide derivative of the classic RGD (Arg-Gly-Asp) sequence, a critical motif for cell adhesion and signaling. This modified compound is engineered for enhanced stability and specificity in targeting integrin receptors, which are pivotal in numerous biological processes. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for applications in drug discovery, biomaterial development, and advanced cell culture studies.

Application

• Integrin Research & Drug Discovery: Serves as a key biochemical tool for studying cell adhesion mechanisms and screening for potential therapeutic agents targeting integrin-mediated pathways.
• Biomaterial Functionalization: Used to coat or modify surfaces of medical devices, implants, and scaffolds to promote specific cellular attachment and tissue integration.
• Cell Culture & Tissue Engineering: Enhances the adhesion and growth of specific cell types in vitro, supporting advanced 3D culture systems and regenerative medicine research.
• Diagnostic Assay Development: Employed in the development of biochemical assays and biosensors for detecting integrin expression or activity.
• Peptide-Based Therapeutic Development: Acts as a lead compound or a targeting moiety in the design of novel peptide therapeutics for oncology, cardiovascular, and inflammatory diseases.

Basic Information

Product Name	Arginine-Glycine-Aspartate-o-Methyltyrosine Amide
CAS No.	123491-58-7
Molecular Formula	C24H38N8O8
Molecular Weight	566.61 g/mol
Synonyms	RGD-o-Methyltyrosine Amide; Arg-Gly-Asp-o-Me-Tyr-NH2; Cyclo(RGDyK) analog; c(RGDyK) derivative; Integrin-binding peptide; Adhesion peptide; RGDoMeTyr-NH2; 4-[[(2S)-2-[[(2S)-2-Amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-5-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid amide
EINECS	Contact for details

Quality Control

Our Arginine-Glycine-Aspartate-o-Methyltyrosine Amide is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development. Certificates of Analysis (COA) detailing purity (by HPLC), peptide content, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.