Description

Meldrum'S Acid-13C is a stable isotope-labeled analog of Meldrum's acid, where the central carbonyl carbon is replaced with the carbon-13 (13C) isotope. This compound is a critical building block and internal standard in advanced analytical chemistry and metabolic research, providing unparalleled accuracy for quantitative analysis and tracer studies. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and academic sectors who require precise molecular tracking and high-fidelity analytical data.

Application

• As a stable isotope-labeled internal standard for the accurate quantification of Meldrum's acid and its derivatives in complex matrices using LC-MS or GC-MS.
• In metabolic pathway tracing and flux analysis studies within pharmaceutical and biochemical research.
• As a specialized precursor for the synthesis of 13C-labeled heterocycles, pharmaceuticals, and complex organic molecules.
• For use in NMR spectroscopy as a tool to simplify spectra and study reaction mechanisms due to the distinct 13C signal.
• In the development and validation of analytical methods to meet rigorous regulatory standards in drug development.
• For environmental fate studies tracking the degradation and transformation of chemical compounds.

Basic Information

Product Name	Meldrum'S Acid-13C
CAS No.	123254-02-4
Molecular Formula	C613CH8O4
Molecular Weight	147.10 g/mol (approx.)
Synonyms	2,2-Dimethyl-1,3-dioxane-4,6-dione-13C; 2,2-Dimethyl-1,3-dioxane-4,6-dione-4-13C; Isopropylidene malonate-13C; Meldrum's Acid-4-13C; Meldrum's Acid Carbonyl-13C; 13C-Labeled Meldrum's Acid; [4-13C]-2,2-Dimethyl-1,3-dioxane-4,6-dione
EINECS	Contact for details

Quality Control

Our Meldrum'S Acid-13C is produced under controlled conditions to ensure exceptional isotopic and chemical purity, meeting the stringent requirements of research and development. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (Atom % 13C), chemical purity (by HPLC/NMR), and identity confirmation. We adhere to rigorous quality testing protocols to guarantee batch-to-batch consistency and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % 13C)	≥ 99%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.