Description

Heptakis-6-(Dimethyl-tert-Butylsilyl)-β-Cyclodextrin is a highly functionalized, organosilylated derivative of β-cyclodextrin designed for advanced research and process chemistry. This compound is engineered to provide enhanced solubility, stability, and selective binding properties compared to native cyclodextrins, making it a powerful tool for molecular encapsulation and chiral separation. It is primarily utilized by pharmaceutical researchers, analytical chemists, and material scientists working on drug delivery systems, catalysis, and sensor development.

Application

• Chiral Stationary Phase (CSP) Development: A key component for high-performance liquid chromatography (HPLC) columns used in the enantiomeric separation of complex pharmaceutical intermediates and active ingredients.
• Drug Solubilization & Delivery: Acts as a sophisticated host molecule to improve the aqueous solubility, stability, and bioavailability of poorly soluble active pharmaceutical ingredients (APIs).
• Catalysis & Synthesis: Serves as a molecular scaffold or chiral auxiliary in asymmetric synthesis and organocatalysis to control reaction stereoselectivity.
• Chemical Sensor Design: Used in the fabrication of selective sensing layers for electrochemical or optical sensors targeting specific guest molecules.
• Material Science: Incorporated into polymers, gels, or coatings to create functional materials with molecular recognition capabilities.
• Reference Standard: Employed as a high-purity analytical standard in method development and quality control for cyclodextrin-based products.

Basic Information

Product Name	Heptakis-6-(Dimethyl-tert-Butylsilyl)-β-Cyclodextrin
CAS No.	123155-03-3
Molecular Formula	C91H182O35Si7
Molecular Weight	~2000.0 g/mol (Contact for exact value)
Synonyms	Heptakis(6-O-(tert-Butyldimethylsilyl))-β-cyclodextrin; 6A-O-tert-Butyldimethylsilyl-β-cyclodextrin (fully substituted); β-Cyclodextrin, heptakis(6-O-(tert-butyldimethylsilyl)) ether; Per-6-tert-butyldimethylsilyl-β-cyclodextrin; TBDMS-β-CD; Heptakis(6-O-TBDMS)-β-CD; 6-O-TBDMS-β-cyclodextrin (heptakis); 123155-03-3
EINECS	Contact for details

Quality Control

Our Heptakis-6-(Dimethyl-tert-Butylsilyl)-β-Cyclodextrin is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity. Quality is verified through a suite of analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your research and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere (e.g., argon or nitrogen) in a desiccator to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.