Description

Octakis-6-(Dimethyl-tert-Butylsilyl)-γ-Cyclodextrin is a highly functionalized, silylated derivative of γ-cyclodextrin, designed to enhance solubility and modify host-guest interaction properties. This specialized chemical is critical for advanced research and development in supramolecular chemistry and pharmaceutical sciences, where precise molecular encapsulation and controlled release are required. It serves as a key intermediate and chiral selector for scientists in pharmaceutical R&D, analytical chemistry, and material science.

Application

• Chiral Stationary Phases (CSPs): Used as a chiral selector in High-Performance Liquid Chromatography (HPLC) and Capillary Electrophoresis (CE) for the separation of enantiomers in pharmaceutical analysis.
• Pharmaceutical Research: Acts as a solubilizing and stabilizing agent for poorly soluble drug candidates, improving their bioavailability and formulation properties.
• Supramolecular Chemistry: Serves as a sophisticated building block for constructing molecular capsules, sensors, and catalysts with tailored cavities.
• Chemical Synthesis: Utilized as a protecting group or a phase-transfer catalyst in organic synthesis due to its lipophilic exterior and hydrophilic cavity.
• Material Science: Incorporated into polymers and coatings to create functional materials with selective absorption or release capabilities.
• Flavor & Fragrance Encapsulation: Employed to stabilize and control the release of sensitive flavor or fragrance compounds in specialty applications.

Basic Information

Product Name	Octakis-6-(Dimethyl-tert-Butylsilyl)-γ-Cyclodextrin
CAS No.	123155-06-6
Molecular Formula	C128H256O40Si8
Molecular Weight	~2595.0 g/mol
Synonyms	Heptakis(6-O-tert-butyldimethylsilyl)-γ-cyclodextrin; γ-Cyclodextrin, octakis(6-O-(1,1-dimethylethyl)dimethylsilyl) ether; Octa-O-(tert-butyldimethylsilyl)-γ-cyclodextrin; Silylated γ-Cyclodextrin; TBDMS-γ-CD; γ-CD TBDMS derivative; 6-O-TBDMS-γ-cyclodextrin; Per(6-O-tert-butyldimethylsilyl)-γ-cyclodextrin
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and functional integrity. Certificates of Analysis (COA) detailing specific batch results are available upon request. We adhere to a strict quality management system to ensure supply reliability and product consistency for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.