Description

Heptakis(2,3-Di-o-Methyl-6-o-tert-Butyldimethylsilyl)-β-Cyclodextrin is a highly functionalized, chemically modified derivative of β-cyclodextrin designed for advanced research and analytical applications. This compound is engineered to provide superior molecular encapsulation and chiral recognition capabilities, making it a critical tool for separation science. It is primarily utilized by researchers and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for enantiomeric separation, catalysis, and solubility enhancement studies.

Application

• Chiral Stationary Phases (CSPs): A key selector for high-performance liquid chromatography (HPLC) and gas chromatography (GC) columns used in the separation of enantiomers for pharmaceutical purity analysis.
• Analytical Reference Standard: Serves as a critical standard in method development and validation for chiral separation protocols in quality control laboratories.
• Host-Guest Chemistry Research: Used in supramolecular chemistry studies to investigate molecular recognition, encapsulation, and the formation of inclusion complexes.
• Catalysis & Synthesis: Acts as a chiral auxiliary or catalyst in asymmetric synthesis to induce stereoselectivity in organic reactions.
• Solubility & Stability Enhancement: Employed to improve the aqueous solubility, bioavailability, and stability of poorly soluble active pharmaceutical ingredients (APIs) in pre-formulation studies.
• Sensor Development: Incorporated into chemical sensors and assays for the selective detection of specific organic molecules or ions based on host-guest interactions.

Basic Information

Product Name	Heptakis(2,3-Di-o-Methyl-6-o-tert-Butyldimethylsilyl)-β-Cyclodextrin
CAS No.	123155-04-4
Molecular Formula	C119H238O35Si7
Molecular Weight	Contact for details
Synonyms	Heptakis(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-β-cyclodextrin; 2,3-di-O-methyl-6-O-tert-butyldimethylsilyl-β-cyclodextrin (heptakis); Permethylated 6-O-TBDMS-β-cyclodextrin; 6-O-TBDMS-2,3-di-O-methyl-β-cyclodextrin; Heptakis(2,3-di-O-methyl-6-O-TBDMS)-β-CD; TBDMS-permethyl-β-cyclodextrin; β-CD-(OTBDMS)7(OMe)14
EINECS	Contact for details

Quality Control

Our Heptakis(2,3-Di-o-Methyl-6-o-tert-Butyldimethylsilyl)-β-Cyclodextrin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.