Description

Phoslactomycin D is a potent and structurally unique natural product belonging to the phoslactomycin family of antibiotics. This compound matters as a highly valuable biochemical tool and research standard for studying protein phosphatase inhibition and cellular signaling pathways. It is primarily needed by researchers and developers in the pharmaceutical and biotechnology sectors for drug discovery, mechanism-of-action studies, and as a reference material for analytical purposes.

Application

• Biochemical Research: Used as a potent and selective inhibitor of protein phosphatases, particularly PP2A, in cell signaling and cancer research.
• Antibiotic Studies: Serves as a reference compound in microbiological research to investigate its mechanism of action against fungi and bacteria.
• Pharmaceutical Development: Acts as a lead compound or intermediate in the discovery and synthesis of novel therapeutic agents targeting infectious diseases and cancer.
• Analytical Standard: Employed as a high-purity certified reference material (CRM) for quality control and method validation in HPLC, LC-MS, and NMR analyses.
• Cell Biology: Utilized in studies of cell cycle regulation, apoptosis, and other cellular processes affected by phosphatase activity.
• Natural Product Chemistry: Important for structural-activity relationship (SAR) studies and the synthesis of novel analogs.

Basic Information

Product Name	Phoslactomycin D
CAS No.	122856-28-4
Molecular Formula	C₂₄H₃₅NO₈P
Molecular Weight	496.51 g/mol
Synonyms	Phoslactomycin D; L-156,602; FR-901512; Antibiotic L 156602; Antibiotic FR 901512; (2E,4E,6E,8E)-9-[(2R,3S,4S,5S,6R)-4,5-Dihydroxy-6-[[(2S,3S)-3-hydroxy-2-[(1E,3E,5E)-7-[(2S,5S)-5-methyl-2-(phosphonooxy)oxan-2-yl]hepta-1,3,5-trien-1-yl]butyl]amino]-2-methyloxan-2-yl]nona-2,4,6,8-tetraenoic acid
EINECS	Contact for details

Quality Control

Our Phoslactomycin D is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and determination of specific optical rotation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep under an inert atmosphere. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Specific Optical Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.