Description

(+/-)-5,6-Epoxyeicosa-8Z,11Z,14Z-Trienoic Acid Methyl Ester CAS NO 122799-12-6 is a specialized methyl ester derivative of an epoxyeicosatrienoic acid (EET), a key class of bioactive lipid mediators. This compound serves as a critical high-purity intermediate and reference standard for research into eicosanoid signaling pathways and their physiological effects. It is primarily utilized by pharmaceutical R&D teams, biochemical researchers, and analytical laboratories focused on cardiovascular, renal, and inflammatory biology.

Application

• Biochemical Research: Used as a reference standard and precursor in studies of cytochrome P450 (CYP) epoxygenase pathways and eicosanoid metabolism.
• Pharmaceutical Development: Serves as a key intermediate in the synthesis of novel drug candidates targeting EET receptors for cardiovascular and anti-inflammatory therapies.
• Analytical Standard: Employed in method development and validation for LC-MS, GC-MS, and HPLC analyses of lipid mediators in biological matrices.
• Cell Signaling Studies: Applied in vitro and in vivo to investigate the role of EETs in vasodilation, angiogenesis, and organ protection.
• Metabolite Synthesis: A starting material for the chemical or enzymatic synthesis of downstream EET metabolites and analogs.

Basic Information

Product Name	(+/-)-5,6-Epoxyeicosa-8Z,11Z,14Z-Trienoic Acid Methyl Ester
CAS No.	122799-12-6
Molecular Formula	C21H34O3
Molecular Weight	334.49 g/mol
Synonyms	5,6-EET Methyl Ester; Methyl 5,6-Epoxyeicosa-8,11,14-trienoate; 5,6-Epoxy-8Z,11Z,14Z-eicosatrienoic Acid Methyl Ester; (±)-5,6-EET-ME; 5,6-Epoxyeicosatrienoic Acid Methyl Ester; Arachidonic Acid 5,6-Epoxide Methyl Ester; 5(6)-Epoxy-8,11,14-eicosatrienoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of (+/-)-5,6-Epoxyeicosa-8Z,11Z,14Z-Trienoic Acid Methyl Ester adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized and tested to ensure high chemical purity and structural integrity. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay (GC)	≥ 90%
Solubility	Soluble in ethanol, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.