Description

2-(4-Trifluoromethylbenzoyl)Pyridine is a high-value fluorinated aromatic ketone building block, recognized for its unique structural motif combining a pyridine ring with a trifluoromethylbenzoyl group. This compound is critical for introducing both lipophilicity and metabolic stability into target molecules, making it a sought-after intermediate in advanced chemical synthesis. It is primarily needed by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags or molecular probes to study biological processes.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring fluorinated aromatic structures.

Basic Information

Product Name	2-(4-Trifluoromethylbenzoyl)Pyridine
CAS No.	122377-19-9
Molecular Formula	C13H8F3NO
Molecular Weight	251.21 g/mol
Synonyms	2-(4-(Trifluoromethyl)benzoyl)pyridine; [4-(Trifluoromethyl)phenyl](pyridin-2-yl)methanone; 2-Pyridyl 4-(Trifluoromethyl)phenyl ketone; α-Pyridyl-4-trifluoromethylphenyl ketone; 2-(4-Trifluoromethyl-benzoyl)-pyridine; 2-(α,α,α-Trifluoro-p-toluoyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-(4-Trifluoromethylbenzoyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ISO standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.