Description

2-(Bromomethyl)-3-Fluoropyridine is a versatile and high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromomethyl and fluorine substituents, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used to construct advanced pyridine-based herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or fluorinated polymers.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or affinity probes for studying biological systems and target engagement.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-(Bromomethyl)-3-Fluoropyridine
CAS No.	122307-44-2
Molecular Formula	C6H5BrFN
Molecular Weight	190.01 g/mol
Synonyms	3-Fluoro-2-(bromomethyl)pyridine; 2-Bromomethyl-3-fluoropyridine; (3-Fluoropyridin-2-yl)methyl bromide; 3-Fluoro-2-pyridinemethyl bromide; 122307-44-2; 3-Fluoro-2-(bromomethyl)pyridine; 2-Pyridinemethyl bromide, 3-fluoro-
EINECS	Contact for details

Quality Control

Every batch of 2-(Bromomethyl)-3-Fluoropyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. Our products undergo rigorous quality testing, including HPLC, GC, NMR, and Karl Fischer titration. A detailed Certificate of Analysis (COA) is available for each lot upon request, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent moisture uptake. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.