Description

4-Fluoro-3,5-Dimethylbenzenesulfonylchloride is a high-purity, specialized aromatic sulfonyl chloride derivative. This compound serves as a critical building block in advanced organic synthesis, enabling the introduction of the sulfonamide functional group. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and pesticides with tailored activity profiles.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology Probes: Employed in the design of activity-based probes and affinity labels for studying protein function.
• Dye and Pigment Manufacturing: Intermediate for producing sulfonated dyes and specialty colorants with enhanced properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP conditions where required.

Basic Information

Product Name	4-Fluoro-3,5-Dimethylbenzenesulfonylchloride
CAS No.	122263-78-9
Molecular Formula	C8H8ClFO2S
Molecular Weight	222.66 g/mol
Synonyms	4-Fluoro-3,5-dimethylbenzene-1-sulfonyl chloride; 3,5-Dimethyl-4-fluorobenzenesulfonyl chloride; 4-Fluoro-3,5-dimethylbenzenesulfonyl chloride; 4-Fluoro-3,5-dimethylphenylsulfonyl chloride; 1-(Chlorosulfonyl)-4-fluoro-3,5-dimethylbenzene; 4-Fluoro-3,5-dimethyl-1-benzenesulfonyl chloride; 4-Fluoro-3,5-dimethylbenzenesulphonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3,5-Dimethylbenzenesulfonylchloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.