Description

2-Bromo-4-Methylbenzotrifluoride is a versatile halogenated aromatic building block characterized by its bromine and trifluoromethyl substituents. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for constructing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the bromine atom serves as a handle for further functionalization.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material in the development of fluorinated organic compounds for electronic displays and optoelectronic devices.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Stille couplings, enabling the construction of complex biaryl structures.
• Organic Synthesis & Chemical Research: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel fluorinated compounds.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments that require specific light-fastness and chemical resistance properties.

Basic Information

Product Name	2-Bromo-4-Methylbenzotrifluoride
CAS No.	121793-12-2
Molecular Formula	C8H6BrF3
Molecular Weight	239.04 g/mol
Synonyms	1-Bromo-2-methyl-5-(trifluoromethyl)benzene; 2-Bromo-α,α,α-trifluoro-p-xylene; 2-Bromo-4-methyl-α,α,α-trifluorotoluene; 4-Methyl-2-bromobenzotrifluoride; (2-Bromo-4-methylphenyl)trifluoromethane; 2-Bromo-4-(trifluoromethyl)toluene; α,α,α-Trifluoro-2-bromo-4-methyltoluene
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Methylbenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.6 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.