Description

3,5-Tetrahydroaldosterone Sulfate is a key sulfate-conjugated metabolite of aldosterone, a primary mineralocorticoid hormone. This compound is of significant value in biochemical research and diagnostic development for studying the renin-angiotensin-aldosterone system (RAAS). It is primarily needed by pharmaceutical R&D laboratories, clinical research organizations, and manufacturers of in-vitro diagnostic (IVD) kits and reference standards.

Application

• Biomarker Research: Critical for quantitative analysis in studies of hypertension, heart failure, and disorders of electrolyte balance.
• Diagnostic Kit Development: Serves as a reference standard or calibrator in immunoassays (ELISA, RIA) and LC-MS/MS methods for aldosterone metabolite profiling.
• Metabolic Pathway Studies: Used to investigate the sulfation pathways and clearance mechanisms of aldosterone in preclinical and clinical models.
• Pharmaceutical Reference Standard: Employed as a high-purity analytical standard for method validation, quality control, and regulatory submissions.
• Endocrinology Research: Essential for understanding mineralocorticoid activity, receptor interactions, and related endocrine disorders.

Basic Information

Product Name	3,5-Tetrahydroaldosterone Sulfate
CAS No.	121699-10-3
Molecular Formula	C21H32O8S
Molecular Weight	444.54 g/mol
Synonyms	3α,5β-Tetrahydroaldosterone 3-sulfate; 18,11-Hemiacetal of 3α,5β-tetrahydroaldosterone 3-sulfate; 3α,5β-Tetrahydroaldosterone sulfate; Aldosterone metabolite sulfate; TH-aldosterone sulfate; 11β,21-Dihydroxy-3,20-dioxopregn-4-en-18-al 3-sulfate (3α,5β-tetrahydro form)
EINECS	Contact for details

Quality Control

Our 3,5-Tetrahydroaldosterone Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via MS and NMR, to ensure it meets the high standards required for research and diagnostic applications. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms to reference
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.