Description

p-Cresol-Methyl-13C CAS NO 121474-53-1 is a stable isotope-labeled analog of p-cresol, where the methyl group is enriched with carbon-13. This compound is essential as a high-purity internal standard and tracer in advanced analytical and research applications, ensuring precise quantification and metabolic pathway elucidation. It is primarily needed by analytical laboratories, pharmaceutical researchers, and chemical manufacturers engaged in isotope dilution mass spectrometry (IDMS), metabolic studies, and the synthesis of labeled complex molecules.

Application

• Internal Standard for Quantitative Analysis: Used in Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) for the accurate measurement of p-cresol in complex matrices like biological fluids, environmental samples, and industrial products.
• Metabolic Tracer Studies: Enables the tracking of metabolic pathways and degradation products in pharmacokinetic, microbiological, and environmental fate studies.
• Pharmaceutical Research & Development: Serves as a critical tool in drug metabolism and disposition (DMPK) studies to understand the biotransformation of compounds containing the cresol structure.
• Synthesis of Labeled Compounds: Acts as a labeled building block for the preparation of more complex carbon-13 labeled intermediates, fine chemicals, or active pharmaceutical ingredients (APIs).
• Quality Control & Method Validation: Employed in the development and validation of robust analytical methods in compliance with Good Laboratory Practice (GLP) and other regulatory guidelines.
• Environmental Analysis: Facilitates the sensitive detection and quantification of cresol pollutants in water, soil, and air samples.

Basic Information

Product Name	p-Cresol-Methyl-13C
CAS No.	121474-53-1
Molecular Formula	C6H4(13CH3)OH
Molecular Weight	109.13 g/mol (approx.)
Synonyms	4-Methylphenol-methyl-13C; 4-(13C)Methylphenol; p-Cresol-13CH3; 1-Hydroxy-4-(13C)methylbenzene; 4-Hydroxy-13C-toluene; Carbon-13 Labeled p-Cresol; [13C]p-Cresol; 121474-53-1
EINECS	Contact for details

Quality Control

Our p-Cresol-Methyl-13C is manufactured under controlled conditions to ensure exceptional isotopic and chemical purity, meeting the stringent requirements of research and analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment, chemical purity (by HPLC/GC), and identity confirmation. We adhere to a rigorous quality management system to guarantee batch-to-batch consistency and reliability for your critical studies.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow crystalline solid or liquid
Identification (IR / NMR)	Conforms to structure
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.