Description

2-Mercapto-6-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its pyridine core substituted with a thiol group and a trifluoromethyl moiety. This combination of structural features makes it a critical intermediate for synthesizing advanced compounds with tailored properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by material scientists exploring specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Precursor: Serves as a versatile precursor for synthesizing specialized ligands in coordination chemistry and catalysis, useful in fine chemical and petrochemical processes.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and electronic materials that require specific fluorine-containing aromatic units.
• Custom Synthesis and Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-Mercapto-6-(Trifluoromethyl)Pyridine
CAS No.	121307-80-0
Molecular Formula	C6H4F3NS
Molecular Weight	179.16 g/mol
Synonyms	6-(Trifluoromethyl)pyridine-2-thiol; 2-Pyridinethiol, 6-(trifluoromethyl)-; 6-(Trifluoromethyl)-2-mercaptopyridine; 2-Mercapto-6-trifluoromethylpyridine; 2-Thiol-6-trifluoromethylpyridine; 6-Trifluoromethyl-2-pyridinethiol; 2-SH-6-CF3-Pyridine
EINECS	Contact for details

Quality Control

Our 2-Mercapto-6-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.