Description

Sphingofungin C is a potent and naturally occurring sphingolipid analog and a specific inhibitor of serine palmitoyltransferase (SPT), the first and rate-limiting enzyme in sphingolipid biosynthesis. This compound is a critical research tool for studying the role of sphingolipids in cellular processes such as apoptosis, cell proliferation, and signal transduction. It is primarily utilized by researchers and scientists in the fields of biochemistry, cell biology, and pharmacology for target validation and mechanistic studies.

Application

• Biochemical Research: As a specific inhibitor of serine palmitoyltransferase (SPT) to study de novo sphingolipid synthesis pathways.
• Cell Biology Studies: For investigating the role of sphingolipids in cell growth, differentiation, and programmed cell death (apoptosis).
• Pharmacology & Drug Discovery: Used as a reference standard and a tool compound for validating novel SPT inhibitors and exploring therapeutic targets related to sphingolipid metabolism.
• Academic & Industrial R&D: Employed in laboratories for fundamental research into lipid biology, membrane structure, and related disease mechanisms.

Basic Information

Product Name	Sphingofungin C
CAS No.	121025-46-5
Molecular Formula	C21H39NO5
Molecular Weight	385.54 g/mol
Synonyms	Sphingofungin C; (2S,3R,4E,6E,8E)-2-Amino-3-hydroxy-4,6,8-octadecatrienoic acid, 10,11-epoxy-9-oxo-; Antibiotic 32102; Serine palmitoyltransferase inhibitor; SPT Inhibitor; LCB2-32102; Contact for details for additional synonyms.
EINECS	Contact for details

Quality Control

Our Sphingofungin C is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) with detailed chromatographic and spectral data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and light-sensitive; allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, Ethanol; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.