Description

Sphingofungin B CAS NO 121025-45-4 is a potent and naturally occurring antifungal agent belonging to the sphingofungin class of compounds. It serves as a critical biochemical tool and a lead compound in antifungal research due to its specific inhibition of serine palmitoyltransferase, a key enzyme in sphingolipid biosynthesis. This product is essential for researchers and developers in the pharmaceutical and biotechnology sectors focused on novel antifungal therapies, metabolic pathway studies, and drug discovery programs.

Application

• Biochemical Research: Used as a specific inhibitor of serine palmitoyltransferase (SPT) to study sphingolipid metabolism and signaling pathways in cell biology and enzymology.
• Antifungal Agent Development: Serves as a reference standard and a lead compound in the discovery and development of new antifungal pharmaceuticals targeting fungal cell membrane synthesis.
• Cell Biology Studies: Employed to investigate the role of sphingolipids in cellular processes such as apoptosis, cell growth, and stress responses.
• Pharmaceutical Reference Standard: Utilized as a high-purity analytical standard for quality control, method development, and identification in pharmaceutical analysis.
• Academic and Industrial R&D: A key reagent in life science research for universities, contract research organizations (CROs), and biotech companies exploring lipid biochemistry.

Basic Information

Product Name	Sphingofungin B
CAS No.	121025-45-4
Molecular Formula	C21H39NO5
Molecular Weight	385.54 g/mol
Synonyms	Sphingofungin B; (2S,3S,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-methyl-6-hexadecenoic acid; Antibiotic 32195; ISP-I analog; Serine palmitoyltransferase inhibitor; LCB2 inhibitor; Sphingofungin.
EINECS	Contact for details

Quality Control

Our Sphingofungin B is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.