Description

3-(3-Fluorophenyl)-1-[2-Hydroxy-4,6-Bis(Phenylmethoxy)Phenyl]-2-Propen-1-One is a specialized fluorinated chalcone derivative, a key intermediate in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which is integral to the development of novel pharmacologically active molecules. It is primarily required by research institutions and pharmaceutical companies engaged in the discovery and development of new chemical entities, particularly for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Fluorinated Compound Library Synthesis: A valuable precursor for creating diverse libraries of fluorinated organic molecules for high-throughput screening.
• Chemical Biology Probes: Employed in the development of molecular probes to study enzyme mechanisms and protein-ligand interactions.
• Material Science Precursor: Can be utilized in the synthesis of advanced organic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic electronics.

Basic Information

Product Name	3-(3-Fluorophenyl)-1-[2-Hydroxy-4,6-Bis(Phenylmethoxy)Phenyl]-2-Propen-1-One
CAS No.	120980-17-8
Molecular Formula	C29H23FO4
Molecular Weight	454.49 g/mol
Synonyms	3-(3-Fluorophenyl)-1-[2-hydroxy-4,6-bis(benzyloxy)phenyl]prop-2-en-1-one; 1-[2-Hydroxy-4,6-bis(phenylmethoxy)phenyl]-3-(3-fluorophenyl)-2-propen-1-one; Fluorinated Chalcone Derivative; 3'-Fluoro-2',4,6'-tribenzyloxychalcone; 120980-17-8; 3-(3-Fluorophenyl)-1-(2-hydroxy-4,6-bis(benzyloxy)phenyl)prop-2-en-1-one
EINECS	Contact for details

Quality Control

Our 3-(3-Fluorophenyl)-1-[2-Hydroxy-4,6-Bis(Phenylmethoxy)Phenyl]-2-Propen-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure high consistency and reliability for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.