Description

3-(Trifluoromethyl)Cyclohexylacetic Acid is a fluorinated organic acid building block of significant interest in advanced chemical synthesis. Its value lies in the unique combination of the cyclohexyl backbone and the electron-withdrawing trifluoromethyl group, which can dramatically influence the physicochemical properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity, stability, and lipophilicity.
• Liquid Crystal & OLED Materials: Acts as a precursor in the synthesis of fluorinated components for electronic display materials, improving dielectric anisotropy and thermal stability.
• Advanced Polymer Modifiers: Incorporated into specialty polymers to impart unique surface properties, chemical resistance, and altered refractive indices.
• Catalyst & Ligand Development: Utilized in organometallic chemistry to create novel chiral ligands and catalysts for asymmetric synthesis.
• Chemical Research & Development: A versatile building block for exploring structure-activity relationships (SAR) in medicinal and material science chemistry.

Basic Information

Product Name	3-(Trifluoromethyl)Cyclohexylacetic Acid
CAS No.	120976-33-2
Molecular Formula	C9H13F3O2
Molecular Weight	210.19 g/mol
Synonyms	3-(Trifluoromethyl)cyclohexaneacetic acid; [3-(Trifluoromethyl)cyclohexyl]acetic acid; 2-[3-(Trifluoromethyl)cyclohexyl]acetic acid; Cyclohexaneacetic acid, 3-(trifluoromethyl)-; α-Cyclohexyl-3-(trifluoromethyl)acetic acid; 3-(Trifluoromethyl)cyclohexyl ethanoic acid
EINECS	Contact for details

Quality Control

Our production of 3-(Trifluoromethyl)Cyclohexylacetic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral GC/HPLC for enantiomeric excess where applicable, to ensure it meets precise customer specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. Due to its acidic nature, ensure containers are made of compatible materials and are properly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.