Description

Trimethylsilyl 2-(Fluorosulfonyl)Difluoroacetate is a specialized organosilicon reagent featuring a unique combination of fluorosulfonyl and difluoroacetate functional groups. This compound is valued for its role as a versatile building block and fluorinating agent in advanced synthetic chemistry. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel fluorinated molecules.

Application

• Pharmaceutical Intermediate: A key reagent for introducing fluorosulfonyl and difluoroacetate moieties into active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and pesticides, where fluorination enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or modifying agent in the synthesis of specialty polymers and coatings with tailored surface properties.
• Fluorination Reagent: Acts as a source of fluorine atoms in organic synthesis for the preparation of complex fluoroorganic compounds.
• Lithium-Ion Battery Electrolyte Additive: Investigated for use in formulating advanced electrolytes to improve battery performance and cycle life.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodological studies and the creation of novel chemical entities.

Basic Information

Product Name	Trimethylsilyl 2-(Fluorosulfonyl)Difluoroacetate
CAS No.	120801-75-4
Molecular Formula	C7H11F3O4SSi
Molecular Weight	276.30 g/mol
Synonyms	2-(Fluorosulfonyl)-2,2-difluoroacetic Acid Trimethylsilyl Ester; (Fluorosulfonyl)difluoroacetic Acid Trimethylsilyl Ester; TMS-DFA; Trimethylsilyl (Fluorosulfonyl)difluoroacetate; Difluoro(fluorosulfonyl)acetic Acid Trimethylsilyl Ester; TMS Ester of (Fluorosulfonyl)difluoroacetic Acid
EINECS	Contact for details

Quality Control

Every batch of Trimethylsilyl 2-(Fluorosulfonyl)Difluoroacetate is produced and analyzed under strict quality management protocols. We ensure high purity and consistency through advanced analytical techniques including NMR, GC, and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.