Description

2-Chloro-1,3-Difluoro-4-Trifluoromethyl-Benzene is a high-value, multi-functional fluorinated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring chlorine, fluorine, and a trifluoromethyl group, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic cores to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorinated phenyl ring enhances lipophilicity and target binding.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, improving dielectric anisotropy and stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart chemical resistance, lower surface energy, and improve thermal properties.
• Organic Synthesis Reagent: A versatile substrate for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution, enabling complex molecule construction.
• Research & Development: Utilized in academic and industrial labs for exploring new synthetic methodologies and developing novel fluorinated compounds.

Basic Information

Item	Details
Product Name	2-Chloro-1,3-Difluoro-4-Trifluoromethyl-Benzene
CAS No.	120770-03-8
Molecular Formula	C7H2ClF5
Molecular Weight	216.54 g/mol
Synonyms	1-Chloro-2,4-Difluoro-5-(Trifluoromethyl)Benzene; 2,4-Difluoro-1-Chloro-5-(Trifluoromethyl)Benzene; 2-Chloro-α,α,α,4,6-Pentafluorotoluene; 4-Trifluoromethyl-2-Chloro-1,3-Difluorobenzene; 5-Chloro-2,4-Difluorobenzotrifluoride; 2-Chloro-1,3-Difluoro-4-(Trifluoromethyl)Benzene; 2-Chloro-1,3-Difluoro-4-(Trifluoromethyl)benzene; 2-Chloro-1,3-Difluoro-4-Trifluoromethylbenzene
EINECS	Contact for details

Quality Control

Our 2-Chloro-1,3-Difluoro-4-Trifluoromethyl-Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical properties is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use and stored away from heat sources and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.55 g/cm³
Boiling Point	~165-170°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.